Wanted to report back that:
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I was successful flashing my gen2 (H series) APIM to MY18.5 calibration using the files @F150Chief provided. It was a really quick process. I used an OBDLink EX.
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Thrilled to say that after doing so, and then setting DE05 Illumination Gateway to C1MCA, the auto-dim toggle appeared in Settings > Display. As usual It defaults to “on”, but toggling it to “off” fixes the flickering issue, just like I used to do with Sync 3.0 (and 3.4.19101). Furthermore, the change persists after shutting the car completely off and back on. Everything is working fine, including the screen backlight turning off with the car and day/night mode transitions. I am running the latest Sync 3.4.22020, but I would guess it likely works on some of the previous builds as well.
Note you don’t need to (and should not) make the other as-built changes balmix proposed for the flickering issue–the DE17 “Delay Gateway Day/Night” 00 → 96, nor the DE00 Illumination FOE → FNA. DE05 is the only change needed (along with MY18.5 calibration on the APIM).
That said, more data points are needed before declaring this fixed. Hopefully other folks can try it and report back.