This can be done with the Syn3 Updater and a cut down version of the maps, as the whole EU package will not fit on a US APIM. Below is a tutorial to read for what is involved, but it is best to use the Syn3 Updater app. You will need to change the region settings in the APIM using FORScan or other program. This will require a quality OBD adapter.
Please note that CyanLabs does not support changing regions.
This tutorial is for informational purposes.
Tutorial: EU Maps to US Car (3.4 Sync, F9 Maps) - Ford / Guides & Info - CyanLabs Official Community