Not if the replacement part is the same as the original. There is really no way to program the buttons other than what type of button assembly is fitted.
Just on the steering wheel? the panel controls are ok?
The SWC button issue existed before the upgrade to Sync 3.4?
Steering wheel controls INOP after update - Ford / Help & Support - CyanLabs Official Community
ACM Sound But No Controls - Ford / Help & Support - CyanLabs Official Community